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Now live: A fully responsive profile. The results of the Oncotype DX Breast Recurrence Score Test, combined with other features of the cancer, can help you make a more informed decision about whether or not to have chemotherapy to treat early-stage, hormone-receptor-positive, HER2-negative breast cancer.
Most early-stage, estrogen-receptor-positive, HER2-negative breast cancers are treated with hormonal therapies, such as an aromatase inhibitor or tamoxifen, after surgery to reduce the risk that the cancer will come back in the future. Whether or not chemotherapy is also necessary has been an area of uncertainty for patients and their doctors.
The Oncotype DX Breast Recurrence Score Test analyzes the activity of 21 genes that can influence how likely a cancer is to grow and respond to treatment. So, the Oncotype DX Breast Recurrence Score Test is both a prognostic test, since it provides more information about how likely or unlikely the breast cancer is to come back, and a predictive test, since it predicts the likelihood of benefit from chemotherapy or radiation therapy treatment.
Based on your age, you and your doctor can use the following ranges to interpret your results for early-stage invasive cancer. You and your doctor will consider the Recurrence Score in combination with other factors, such as the size and grade of the cancer and the number of hormone receptors the cancer cells have many vs.
Together, you can make a decision about whether or not you should have chemotherapy. DCIS is the most common form of non-invasive breast cancer. DCIS usually is treated by surgically removing the cancer lumpectomy in most cases.
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